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CAR T Therapy for certain Autoimmune diseases

When it comes to combating Autoimmune diseases, researchers believe there may be potential in CAR T cell therapy.

Just as T cells can be taught to attack cancerous cells, they may also be taught to attack malfunctioning immune cells. Researchers believe that, when used to address autoimmune diseases, CAR T cell therapy may help the body destroy malfunctioning immune cells and potentially lead to improvement or remission.

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Patient Resources

  • CAR T cell therapy (Chimeric Antigen Receptor (CAR) T Cell) is a type of immunotherapy that is most commonly given to individuals who have specific types of cancer.  BMS is evaluating CAR T therapy in study participants for its potential effectiveness in treating certain autoimmune diseases.  In the case of certain cancers, CAR T cell therapy is used to teach a patient’s T cells how to target and destroy the cancerous cells in their body.1​

    • A CAR is a special receptor (a structure that receives a message to act a certain way in the body) created in a laboratory. CARs are made to connect with certain proteins on a cell.​
    • Autologous T cells are a kind of white blood cell, which attacks foreign invaders in the body.​

     

    1​dana-farber.org/cellular-therapies-program/car-t-cell-therapy/faq-about-car-t-cell-therapy

  • T cell

    A key fighter in your immune system.

    CAR

    A specific receptor (or hook) that is added to the T cell.

    CAR T CELL

    Your body’s T cell with the CAR added is now called a CAR T cell.