Medications are available that can slow the progression of melanoma. However, not all melanomas respond, and the side effects sometimes outweigh the benefits.
That’s why researchers are working hard to develop more options—like those under investigation in our clinical research program.
On this page you’ll find information about melanoma clinical trials in general, the current treatment landscape, and active clinical trials for melanoma, including stage III (stage 3) melanoma and stage IV (stage 4) melanoma (also called advanced or metastatic melanoma).
Watch our short video to find out more about melanoma and why we are conducting clinical research into the condition.
Clinical trials in detail
Our "Participant's Discussion Guide to Cancer Clinical Trials" has information about how clinical trials work.Download the guide
Why do people take part in clinical studies?
People take part in clinical trials for a variety of reasons that are unique to them. Some people may decide to take part because they want to help researchers understand a disease better, or find potential new treatments for people in the future. Sometimes enrolling in a clinical trial gives people access to an investigational drug – something that may be of interest when all approved treatment options have been exhausted.More FAQs
Are clinical trials safe?
The safety of participants is the number one priority in any clinical trial. While no one can guarantee that an investigational drug won’t cause any side effects, the health of every participant is monitored closely by the trial team to ensure that any side effects that do arise are managed effectively.More FAQs
How might my loved one be affected by participating in a clinical trial?
Clinical trials often involve additional doctor visits, and these may impact your loved one’s daily routine. Some participants may also experience discomfort from trial procedures or side effects from the investigational drug.More FAQs
My loved one is participating in a clinical trial. How can I support them?
There are lots of ways to support a loved one as they take part in a melanoma clinical trial. Transporting your loved one to their clinic visits or reminding them of things they need to bring with them may help them manage their stress. You could even take notes of symptoms they experience on their behalf, as these are often helpful to researchers. And of course, supporting your loved one by simply being present, listening and offering encouragement is also really valuable.More FAQs
Thank you for considering a melanoma clinical trial
Hear from patients with melanoma as they share experiences
"I noticed a red spot on my shoulder and didn't think too much about it, but after a few more days it didn't change. Nancy recommended that I probably ought to get it checked"
"I noticed a red spot on my shoulder and didn't think too much about it, but after a few more days it didn't change. Nancy recommended that I probably ought to get it checked"View Story
"The medical oncologist did lay out exactly what was going to happen if I did go through this clinical trial, so there weren't any surprises"
"The medical oncologist did lay out exactly what was going to happen if I did go through this clinical trial, so there weren't any surprises"View Story
A diagnosis of melanoma can be very difficult. Our online community is a place for patients and caregivers to share experiences and offer support. It brings people facing melanoma together.Join the conversation