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Phase 1
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18+Age Range
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1Locations
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Not Yet Recruiting
Not Yet Recruiting
A Study of Absorption, Metabolism, and Elimination CC-90010 in Participants With Advanced Solid Tumors
The purpose of this study is to assess the absorption, metabolism, and elimination of CC-90010 and its metabolites following a single oral dose of radiolabeled CC-90010 in participants with advanced solid tumors.
Inclusion Criteria: - Males ≥ 18 years of age - Has histological or cytological confirmation of advanced solid tumors including those who have progressed on standard anticancer therapy or for whom no other approved conventional therapy exists - Eastern Cooperative Oncology Group Performance Status (ECOG PS) of 0 to 1 Exclusion Criteria: - Persistent diarrhea National Cancer Institute Common Terminology Criteria for Adverse Events (NCI CTCAE) Grade ≥ 2 - History of concurrent second cancers requiring active and ongoing systemic treatment Other protocol-defined inclusion/exclusion criteria apply
Experimental: Part 1: CC-90010 followed by [14C]CC-90010
Experimental: Part 2: CC-90010