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Szukaj Study Connect
  • NCT06618287

Recruiting

A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of BMS-986507 Combinations in Adult Participants With Advanced Solid Tumors - CA244-0001

Zaktualizowano: 16 marzec, 2026   |   ClinicalTrials.gov

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Szczegóły badania

  • Phase 1/Phase 2

    Etap

  • Płeć

  • 18+

    Zakres wieku

  • 53

    Lokalizacje

  • Recruiting

Opcje leczenia

Grupy badania
PRZYPISANA INTERWENCJA
Experimental: Group A
Drug: BMS-986507, Osimertinib
Experimental: Group B
Drug: BMS-986507, Pembrolizumab
Experimental: Group C
Drug: Nivolumab, BMS-986507
Experimental: Group D
Drug: Pumitamig, BMS-986507
Experimental: Group E
Drug: Pumitamig, BMS-986507

Kluczowe kryteria kwalifikacyjne

Inclusion Criteria - Participants must have at least one measurable lesion per response evaluation criteria in solid tumors. - Participants must have an Eastern Cooperative Oncology Group Performance Status of 0 or 1. - Participants must have a life expectancy of at least 3 months at the time of the first dose. Exclusion Criteria - Participants must not have any mixed Small Cell Lung Cancer (SCLC) and Non-Small Cell Lung Cancer (NSCLC) histology. - Participants must not have any untreated symptomatic central nervous system (CNS) metastases. - Participants must not have a history of serious recurrent infections. - Participants must not have a history of severe heart disease. - Other protocol-defined Inclusion/Exclusion criteria apply.