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Szukaj Study Connect
  • NCT03459222

Active, Not Recruiting

An Investigational Study of Immunotherapy Combinations in Participants With Solid Cancers That Are Advanced or Have Spread - CA224-048

Zaktualizowano: 14 wrzesień, 2023   |   ClinicalTrials.gov

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Szczegóły badania

  • Phase 1/Phase 2

    Etap

  • Płeć

  • 18+

    Zakres wieku

  • Active, Not Recruiting

Opcje leczenia

Grupy badania
PRZYPISANA INTERWENCJA
Experimental: Arm A
Biological: Nivolumab, Relatlimab Drug: BMS-986205
Experimental: Arm B
Biological: Relatlimab, Ipilimumab, Nivolumab

Kluczowe kryteria kwalifikacyjne

For more information regarding Bristol Myers Squibb Clinical Trial participation, please visit www.BMSStudyConnect.com Inclusion Criteria: - Histologic or cytologic confirmation of an incurable solid malignancy that is advanced (metastatic and/or unresectable), with measurable disease per RECIST v1.1 - Available tumor tissue for biomarker analysis - Eastern Cooperative Oncology Group Performance Status (ECOG) status of 0 or 1 Exclusion Criteria: - Participants with known or suspected uncontrolled CNS metastases or with the CNS as the only site of active disease - Participants with a history of interstitial lung disease (ILD) / pneumonitis - Prior malignancy active within the previous 3 years except for locally curable cancers that have been cured, such as basal or squamous cell skin cancer Other protocol defined inclusion/exclusion criteria could apply