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Cerca in Study Connect

Active, Not Recruiting

A Study Evaluating Potential Disease-Mediated Drug-Drug Interaction in Adult Participants With Active Eosinophilic Esophagitis Receiving Cendakimab - CC-93538-DDI-001

Aggiornato: 26 novembre, 2024   |   ClinicalTrials.gov

Celgene e’ interamente controllata da Bristol-Myers Squibb Company 

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Dettagli della sperimentazione

  • Phase 1

    Fase

  • Sesso

  • 18-75

    Fascia d'età

  • Active, Not Recruiting

Opzioni di trattamento

Bracci dello studio
TERAPIA ASSEGNATA
Experimental: Administration of Cendakimab and Cytochrome P450 (CYP) substrates
Drug: Cendakimab, CYP substrates

Principali criteri di idoneità

Inclusion Criteria: - Active Eosinophilic esophagitis (EoE) with histologic evidence as a peak count of ≥ 15 eosinophils per higher-power field at any 2 levels of the esophagus - Previously received an adequate trial of proton-pump inhibitor medication that did not provide complete response to EoE - EoE symptoms documented in daily diary during the screening period Exclusion Criteria: - On a regimen of therapeutic anticoagulation - Demonstrates evidence of immunosuppression or is receiving systemic immunosuppressive or immunomodulating drugs - Currently receiving a high potency topical corticosteroid for dermatologic use Other protocol-defined inclusion/exclusion criteria apply

Ti consigliamo vivamente di contattare BMS per segnalare gli effetti collaterali (eventi avversi)
Qui vengono definiti gli effetti collaterali (eventi avversi) e altri eventi da segnalare
Segnala effetti collaterali (eventi avversi) o reclami sulla qualità del prodotto: informazioni mediche

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