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  • NCT06955741

Recruiting

A Study to Assess Drug Levels, Tolerability and Absolute Biological Availability of Single-dose of BMS-986446 in Healthy Participants - CN008-0026

Updated: 16 May, 2025   |   ClinicalTrials.gov

Print Friendly Summary

CONSIDERING THIS TRIAL?
Print this page and the trial guide to help you talk with your doctor.
Use the Study Participant's Guide to navigate the process of participating in a clinical trial. Understand key factors to consider before deciding and get questions to ask your healthcare team.
Print this page CN008-0026
Download Study Participant’s Guide

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Trial Details

  • Phase 1

    Phase

  • Gender(s)

  • 18-65

    Age Range

  • 1

    Location(s)

  • Recruiting

Treatment Options

Study Arms
ASSIGNED INTERVENTION
Experimental: Arm A
Drug: BMS-986446 IV, Acetaminophen, Loratadine
Experimental: Arm B
Drug: BMS-986446 SC, Acetaminophen, Loratadine

Key Eligibility Criteria

Inclusion Criteria: - Participants must have a Body Mass Index (BMI) of 18.0 to 30.0 kg/m2. - Participants must be healthy as determined by medical history, physical examination, neurological examination, vital signs, 12-lead ECG, C-SSRS, and clinical laboratory evaluations. Exclusion Criteria: - Participants must not have clinically significant gastrointestinal, renal, hepatic, broncho-pulmonary, neurological, psychiatric, cardiovascular, endocrinological, immune-mediated disorder, hematological, ongoing allergic disorder requiring treatment, metabolic disorder, cancer, or cirrhosis. - Participants must not have prior exposure to BMS-986446 (PRX005). - Other protocol-defined Inclusion/Exclusion criteria apply.

If you want to report a side effect, you can report directly to the Danish Medicines Agency via the website www.meldenbivirkning.dk
We recommend that you also contact BMS to report side effects.
Side effects and other reportable events are defined here
Report side effects or product quality complaints: Medical Information

466-DK-2200001