Inclusion Criteria
- Participants must be healthy as determined by no clinically significant deviation
from normal in medical history, physical examination, vital signs, 12-lead ECGs, and
clinical laboratory determinations in the opinion of the investigator.
- Participants must be willing and able to complete all study-specific procedures and
visits.
- Participants must have a body mass index of 18.0 kg/m2 through 32.0 kg/m2,
inclusive, and total body weight ≥ 50 kg (110 lb).
Exclusion Criteria
- Participants must not have any significant acute or chronic medical illness that
presents a potential risk to the participant and/or may compromise the objectives of
the study, including a history of/or acute liver disease in the opinion of the
Investigator.
- Participants must not have evidence of organ dysfunction or any clinically
significant deviation from normal in physical examination, vital signs, 12-lead ECG,
or clinical laboratory determinations beyond what is consistent with the population
reference ranges in the opinion of the investigator.
- Participants must not have any history of severe reaction to a drug (eg,
anaphylactic, anaphylactoid, Stevens-Johnson, angioedematous), or adverse or
allergic/hypersensitivity reaction to multiple drugs.
- Other protocol-defined Inclusion/Exclusion criteria apply.
