Inclusion Criteria:
- Participants must have an ECOG performance status of 0 to 1.
- Participants must have measurable disease by RECIST v1.1 (radiologically measured by
the Investigator).
- Participants must have documented histologically or cytologically confirmed
advanced, unresectable/metastatic solid tumors, including NSCLC, HNSCC, TNBC, and
HR+/HER2- breast cancer.
Exclusion Criteria:
- Participants must not have untreated CNS metastases. Participants are eligible if
CNS metastases have been treated and do not require immediate treatment or have been
treated and have neurologically returned to baseline (except for residual signs or
symptoms related to the CNS treatment).
- Participants must not have concurrent malignancy (present during Screening)
requiring treatment or history of prior malignancy active within 2 years prior to
treatment assignment.
- Participants must not have history of serious recurrent infections.
- Participants must not have impaired cardiac function or history of severe heart
disease.
- Other protocol-defined inclusion/exclusion criteria apply.
