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Have you recently been diagnosed with breast cancer?

NOW ENROLLING:
Find out if you are eligible
for a clinical trial.

The facts about breast cancer





Know your breast cancer subtype

Be sure to ask your doctor questions about your diagnosis and the type of breast cancer you have. Below are some breast cancer subtypes that may help you understand your subtype of cancer.

Knowing which type of breast cancer you have helps doctors decide how to treat it. Different breast cancer subtypes are treated in different ways.

Your participation in clinical trials that focus on tumours with these characteristics may help pave the way to develop more potential treatments for future patients with the same tumours.



ER+/HER2- BREAST CANCER (oestrogen receptor positive - sometimes referred to as HR+ or Hormone Receptor positive / human epidermal growth factor receptor 2-positive)

This is a subtype of breast cancer that cancer cells test positive for a receptor proteins that bind to oestrogen (ER) and test negative for a protein called human epidermal growth factor receptor 2 (HER2). This subtype of breast cancer is sensitive to treatment with anti-oestrogen hormone (endocrine) therapies.
 

HER2+ BREAST CANCER (human epidermal growth factor receptor 2-positive)

This is a subtype of breast cancer that cancer cells test positive for HER2. This protein promotes the growth of cancer cells.  HER2-positive breast cancers tend to be aggressive and are sensitive to HER2-directed therapies.
 

TRIPLE-NEGATIVE BREAST CANCER (ER-, PR-, HER2-)

This is a subtype of breast cancer that cancer cells test negative for ER, a receptor protein that binds to progesterone (PR) and HER2.  This subtype of breast cancer tends to grow and spread faster than other types of breast cancers and are not sensitive to endocrine therapies and HER2-directed therapies.



Clinical trial participation: getting started

If you decide you are ready to be a part of a clinical trial, but are unsure where to start, completing the pre-screener questionnaire is the first step. This questionnaire will include questions about your diagnosis that will help find clinical trials that you may match to.

You may be nervous at first, but taking action by completing this questionnaire is the first step in potentially helping others by contributing to breast cancer research. If you do decide to enter a clinical trial, you are free to change your mind about participating at any point during the trial.



Available Clinical Trials

Below you will find a list of clinical trials that are sponsored by Bristol Myers Squibb (BMS). Click the “View Trial Details” links below to get more information about each trial. From the top of any trial page, click the purple “Pre-Screen Now” button to answer a few questions and find out if you match to a clinical trial. If you are not a match for a trial sponsored by BMS and you are a match for a trial sponsored by another company, you will be shown those trials to consider.

Breast cancer: myths vs facts

While a lot of information exists about breast cancer, some of what you have heard may not be accurate. Below is a list of some common myths and facts about breast cancer.



The importance of caregivers

If you are helping your family member or friend through cancer treatment, you are a caregiver. This may mean helping with daily activities such as going to the doctor or making meals. It could also mean coordinating services and care. Or it may be giving emotional and spiritual support.

If you are caring for someone in a clinical trial, there are many things you can do to support them as they participate in the study, such as:.

  • Helping schedule and keeping track of study visits
  • Giving rides to study visits for treatment
  • Ensuring study medication is taken according to directions from the clinical trial study team
  • Taking notes during study visits
  • Being sure follow-up visits are scheduled and kept
  • Planning in advance what activities your loved one may want to do while receiving infusions, if applicable, and bringing any items needed for those activities to treatment visits
SELECTED SUPPORT ORGANIZATIONS AND DISEASE INFORMATION
Bristol Myers Squibb is not affiliated with nor endorses any of the listed organizations. The information/links provided by Bristol Myers Squibb are meant for informational purposes only and are not meant to replace a physician's medical advice or imply endorsement.

References:

1. American Cancer Society. Global Cancer Facts & Figures 4th Edition. Available at: https://www.cancer.org/content/dam/cancer-org/research/cancer-facts-and-statistics/global-cancer-facts-and-figures/global-cancer-facts-and-figures-4th-edition.pdf. Accessed February 24, 2020. 2. AACR Publications/Cancer Research/Abstract 4191: The Worldwide female breast cancer incidence and survival, 2018; Zoubida Zaidi and Hussain Adlane Dib; DOI: 10.1158/1538-7445. AM2019-4191. Published July 2019. 3. ABC Global Alliance. Breast cancer worldwide. Available at: https://www.abcglobalalliance.org/articles/breast-cancer-worldwide/. Accessed February 24, 2020. 4. American Cancer Society. Breast Cancer Facts & Figures 2019-2020.  Available at: https://www.cancer.org/content/dam/cancer-org/research/cancer-facts-and-statistics/breast-cancer-facts-and-figures/breast-cancer-facts-and-figures-2019-2020.pdf. Accessed February 28, 2020. 5. Stapleton SM, Oseni TO, Bababekov YJ, et al. JAMA Surg. 2018;153:594-595. 

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