Inclusion Criteria
- Healthy male and female individual(s) not of childbearing potential (INOCBP)
participants of any race or ethnicity, as determined by no clinically significant
findings in medical history, physical examination, 12-lead ECG, or vital signs as
determined by the investigator or designee.
- Potassium, magnesium, and calcium at or above the lower limit of normal. For other
clinical laboratory parameters, no clinically significant findings as determined by
the investigator or designee.
- Must have a body mass index between 18 and 30 kg/m2 (inclusive) and body weight ≥ 50
kg at the time of signing the ICF.
Exclusion Criteria
- History of clinically significant acute or chronic medical illness, such as
endocrine, gastrointestinal (GI), cardiovascular, peripheral vascular,
hematological, hepatic, immunological, renal, respiratory, neoplastic, or
genitourinary abnormalities/diseases as determined by the investigator or designee.
- History of GI disease or surgery that could possibly affect drug absorption,
distribution, metabolism, and excretion (ADME) (eg, bariatric procedure,
cholecystectomy). Uncomplicated appendectomy and hernia repair are acceptable.
- Gilbert's syndrome.
- Other protocol-defined Inclusion/Exclusion criteria apply.
