Inclusion Criteria:
- Histologically or cytologically confirmed locally advanced unresectable, metastatic,
or recurrent malignant tumor. Eligible tumor types are non-small cell lung cancer
(NSCLC), renal cell carcinoma (RCC), pancreatic ductal adenocarcinoma (PDAC),
gastric/gastroesophageal junction, castration-resistant prostate cancer (CRPC),
ovarian, squamous cell carcinoma of the head and neck (SCCHN), bladder, melanoma,
mesothelioma, triple negative breast cancer (TNBC), and soft tissue sarcoma, except
for participants with tumors with central nervous system (CNS) metastases as the only
site of active disease
- Measurable disease by Response Evaluation Criteria in Solid Tumors version 1.1 (RECIST
v1.1), Prostate Cancer Working Group 3 (PCWG3) (for prostate cancer), or modified
Response Evaluation Criteria in Solid tumors (mRECIST) (for mesothelioma)
- Eastern Cooperative Oncology Group Performance Status of 0 or 1
- Adequate organ function
Exclusion Criteria:
- Prior organ or tissue allograft
- Leptomeningeal metastases
- Untreated CNS metastases
- Serious or uncontrolled medical disorders
Other protocol-defined inclusion/exclusion criteria apply
