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Find a Clinical Trial

Melanoma left its mark on you, now leave your mark on Melanoma.

About our melanoma trial(s)

Medications are available that can slow the progression of melanoma. However, not all melanomas respond, and the side effects sometimes outweigh the benefits.

That’s why researchers are working hard to develop more options—like those under investigation in our clinical research program.

On this page you’ll find information about melanoma clinical trials in general, the current treatment landscape, and active clinical trials for melanoma, including stage III (stage 3) melanoma and stage IV (stage 4) melanoma (also called advanced or metastatic melanoma).

Why we conduct melanoma clinical trials

Watch our short video to find out more about melanoma and why we are conducting clinical research into the condition.

Clinical trials in detail

Our "Participant's Discussion Guide to Cancer Clinical Trials" has information about how clinical trials work.

Download the guide

Melanoma by the Numbers

Facts and figures about Melanoma

Discussing melanoma with your doctor

Topics you might want to discuss with your doctor,

Download discussion guide

Supporting your loved one with melanoma

CA224-047

Recruiting

A Study of Relatlimab Plus Nivolumab Versus Nivolumab Alone in Participants With Advanced Melanoma

View Trial Details

CA045-001

Recruiting

A Study of NKTR-214 Combined With Nivolumab vs Nivolumab Alone in Participants With Previously Untreated Inoperable or Metastatic Melanoma

View Trial Details

CA209-8KX

Recruiting

A Study of Subcutaneous Nivolumab Monotherapy With or Without Recombinant Human Hyaluronidase PH20 (rHuPH20)

Recruitment is currently paused for this study.

View Trial Details

CA209-8FC

Recruiting

A Study to Compare Nivolumab Drug Product Process D to Nivolumab Drug Product Process C in Participants With Stage IIIa/b/c/d or Stage IV Melanoma After Complete Resection

Screening has been met.

View Trial Details

Active Melanoma Trial(s)

Thank you for considering a melanoma clinical trial

CA224-020

Recruiting

An Investigational Immuno-therapy Study to Assess the Safety, Tolerability and Effectiveness of Anti-LAG-3 With and Without Anti-PD-1 in the Treatment of Solid Tumors

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CA209-234

Recruiting

Pattern of Use and Safety/Effectiveness of Nivolumab in Routine Oncology Practice

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CA184-487

Recruiting

Yervoy Pregnancy Surveillance Study

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CA224-048

Recruiting

An Investigational Study of Immunotherapy Combinations in Participants With Solid Cancers That Are Advanced or Have Spread

View Trial Details

CA224-047

Recruiting

A Study of Relatlimab Plus Nivolumab Versus Nivolumab Alone in Participants With Advanced Melanoma

View Trial Details

CA045-001

Recruiting

A Study of NKTR-214 Combined With Nivolumab vs Nivolumab Alone in Participants With Previously Untreated Inoperable or Metastatic Melanoma

View Trial Details

CA209-8KX

Recruiting

A Study of Subcutaneous Nivolumab Monotherapy With or Without Recombinant Human Hyaluronidase PH20 (rHuPH20)

Recruitment is currently paused for this study.

View Trial Details

CA209-8FC

Recruiting

A Study to Compare Nivolumab Drug Product Process D to Nivolumab Drug Product Process C in Participants With Stage IIIa/b/c/d or Stage IV Melanoma After Complete Resection

Screening has been met.

View Trial Details

CA209-76K

Recruiting

Effectiveness Study of Nivolumab Compared to Placebo in Prevention of Recurrent Melanoma After Complete Resection of Stage IIB/C Melanoma

View Trial Details

CA209-76U

Recruiting

A Study Evaluating the Drug Levels of Iplimumab Given Under the Skin Alone and in Combination With Nivolumab in Multiple Tumor Types

View Trial Details

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