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The TYK2/STAT Pathway Overview

Follow along to explore more about the role of TYK2

Explore the TYK2/JAK Pathway

Play the video to learn more about the role of the TYK2/JAK pathway

Tyrosine kinase 2 (TYK2), a non- receptor intracellular signaling kinase, mediates signaling pathways that are critical in the cycle of chronic inflammation in immune mediated diseases 

Cytokines mediated by the TYK2/JAK Pathway

Learn More (PDF)

TYK/JAK PATHWAY OVERVIEW1-4

1. Baker KF et al. Ann Rheum Dis. 2018;77:175-187. 2. Gillooly K et al. Poster presentation at ACR/ARHP 2016. Abstract 11L. 3. Jiang L et al. J Biol Chem. 2008;283:28066-28073. 4. Xie J et al. J Biol Chem. 2002;277:14020-14030.

 

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