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BMS Not Yet Recruiting Study icon

Not Yet Recruiting

Trial ID CV018-014  |   NCT04464577

A Study to Evaluate the Effect of Fluconazole, Bupropion, or Itraconazole on the Drug Levels and Safety of BMS-986235

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Sorry, this study is not yet accepting participants.
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Summary

  • Phase 1
  • Male and Female Gender icon
  • 18-65
    Age Range
  • 2
    Locations
  • BMS Not Yet Recruiting Study icon
    Not Yet Recruiting

Overview

This study will evaluate the effect of inhibitors, at steady state, on the drug levels, safety, and tolerability of BMS-986235 when taken by healthy participants. The inhibitors to be utilized in this study are fluconazole, bupropion, and itraconazole.

Key Eligibility Criteria

For more information regarding Bristol-Myers Squibb Clinical Trial participation, please visit www.BMSStudyConnect.com. Inclusion Criteria: - Body mass index of 18.0 kg/m2 to 32.0 kg/m2, inclusive, at screening. - Males and females must agree to follow specific methods of contraception, if applicable. - Healthy participants, as determined by no clinically significant deviation from normal in physical examination, ECGs, and clinical laboratory determinations, and no significant findings in medical history. Exclusion Criteria: - Women of childbearing potential (WOCBP), women who are pregnant or breastfeeding - Inability to tolerate oral medication - Known previous exposure to BMS-986235. Other protocol-defined inclusion/exclusion criteria apply

Treatment Options

Study Arms

ASSIGNED INTERVENTION

Study Arms

Experimental: Arm A: BMS-986235+Fluconazole

ASSIGNED INTERVENTION
  • Drug: BMS-986235 Drug: Fluconazole

Study Arms

Experimental: Arm B: BMS-986235+ Bupropion

ASSIGNED INTERVENTION
  • Drug: Bupropion Drug: BMS-986235

Study Arms

Experimental: Arm C: BMS-986235+ Itraconazole

ASSIGNED INTERVENTION
  • Drug: BMS-986235 Drug: Itraconazole
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Have questions? Live support is available 24/7 - Call 855-907-3286 or email clinical.trials@bms.com

Have questions? Live support is available 24/7 -
Call 855-907-3286 or email clinical.trials@bms.com