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Not Yet Recruiting

A Study to Assess the Pharmacokinetics, Safety and Tolerability of Single-dose Adagrasib (BMS-986503) in Healthy Participants of Japanese Descent - CA239-0028

Mis à jour: 20 juillet, 2026   |   ClinicalTrials.gov

Résumé imprimable

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Détails de l’essai

  • Phase 1

    Phase

  • Sexe(s)

  • 18-60

    Tranche d’âge

  • 1

    Site(s)

  • Not Yet Recruiting

Options de traitement

Bras de l’étude
INTERVENTION ASSIGNÉE
Experimental: Adagrasib
Drug: Adagrasib

Principaux critères d’éligibilité

Inclusion Criteria: - Participants must be of Japanese descent (both biological parents of the participant are ethnically Japanese). - Participants must be healthy adult without clinically significant deviation from normal in medical history, PE, 12-lead ECG, vital sign measurements, and clinical laboratory assessments as determined by the investigator. - Participants must have Body mass index of 18.0 kg/m2 to 32.0 kg/m2. - Participants must have Total body weight ≥ 50 kg. Exclusion Criteria: - Participants must not have significant history or clinical manifestation of any metabolic, allergic, dermatological, renal, hematological, pulmonary, cardiovascular, gastrointestinal, neurological, respiratory, endocrine, or psychiatric disorder, as determined by the investigator. - Other protocol defined Inclusion/Exclusion criteria apply.