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Active, Not Recruiting

A Study to Evaluate the Effect of Omeprazole on the Pharmacokinetics of BMS-986205 in Healthy Participants - CA017-089

Updated: 21 June, 2019   |   ClinicalTrials.gov

Print Friendly Summary

Print this page and the trial guide to help you talk with your doctor.
Use the Study Participant's Guide to navigate the process of participating in a clinical trial. Understand key factors to consider before deciding and get questions to ask your healthcare team.

Trial Details

  • Phase 1


  • Gender(s)

  • 18-50

    Age Range

  • Active, Not Recruiting

Treatment Options

Study Arms
Experimental: BMS-986205 + Omeprazole
Drug: omeprazole Drug: BMS-986205

Key Eligibility Criteria

Inclusion Criteria: - Health male and female participants (not of childbearing potential) as determined by no clinically significant deviation from normal in medical history, physical examination, ECGs, and clinical laboratory determinations - normal renal function at screening as evidenced by an estimated glomerular filtration rate (GFR) greater than or equal to (>=) 80 milliliter per minute per 1.73 meter square (mL/min/1.73 m^2) - Body mass index (BMI) of 18.0 kilogram per meter square (kg/m^2) to 32.0 kg/m^2 - Women participants must have documented proof that they are not of childbearing potential Exclusion Criteria: - Women who are of childbearing potential or breastfeeding - Active tuberculosis (TB) requiring treatment or documented latent TB within the previous 3 years - Concomitant use of strong inhibitors or strong inducers of CYP3A4 - Evidence of organ dysfunction or any clinically significant deviation from normal in physical examination, vital signs, ECG, or clinical laboratory determinations beyond what is consistent with the target population

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